Browse the evidence

Bariatric surgery provides clinically significant and sustained weight loss for individuals with obesity.

Bariatric surgery should be considered for patients needing significant and lasting weight loss.

Modest weight loss leads to improvements in glycemic levels, reducing the risk of diabetes-related complications and comorbidities.

Practitioners should encourage modest weight loss in obese T2D patients to improve glycemic control.

Diet plays an important role in the effective management of type 1 diabetes and type 2 diabetes.

Practitioners should emphasize dietary interventions in diabetes management.

The recent European Society of Cardiology guidelines provide up-to-date recommendations for managing diabetes and cardiovascular risk.

Practitioners should refer to the latest guidelines for effective diabetes management.

At 12 months, 92.1% of patients achieved an HbA1c reduction, with a mean change of −3.8 ± 2.8%.

Practitioners can expect significant improvements in glycemic control with structured follow-up.

Face-to-face interventions demonstrated a significant 46% risk reduction in T2DM incidence and a 46% increase in the reversion to normoglycemia compared with the control group.

Practitioners should prioritize face-to-face interventions for effective T2DM prevention and normoglycemia reversion.

Digital health interventions were associated with a 12% risk reduction in T2DM incidence compared with the control group.

Digital health interventions may offer some benefit, but practitioners should be cautious due to the lack of significant evidence.

Blended interventions combining digital and face-to-face approaches suggested a 37% risk reduction in T2DM incidence and an 87% increase in the reversion to normoglycemia.

Blended interventions may be highly effective and should be considered in T2DM prevention strategies.

Integrating continuous glucose monitoring (CGM) with a digital weight management program produced a 0.46% greater reduction in HbA1c% compared to usual care.

Healthcare providers can consider integrating CGM with weight management programs for better glycemic control.

Significant improvements were observed in cardiometabolic risk markers, mental health, and exercise capacity among participants.

Enhancing physical activity can lead to improved health outcomes in at-risk populations.

Six weeks of physiotherapist-led structured physical exercise program (SPEP) improved glycemic control in adults with type 2 diabetes mellitus (T2DM).

Incorporating structured exercise programs can enhance glycemic control in diabetic patients.

Over a 2-year period, carbohydrate restriction can lead to remission and cure of T2DM.

Long-term carbohydrate restriction may be an effective approach for achieving remission in T2DM.

Personalized nutrition counseling tailored to metabolic phenotypes may benefit insulin sensitivity and cardiovascular risk factors.

Practitioners should consider tailoring nutrition advice based on individual metabolic profiles to improve health outcomes.

Personalized weight management strategies should account for individual metabolic and hormonal differences.

Practitioners should consider individual metabolic profiles when designing weight management plans.

Precision approaches can help tailor weight management plans to an individual's unique metabolic profile.

Implementing precision nutrition can enhance the effectiveness of weight management strategies.

Extreme dieting trends have negative impacts on health and eating behaviors.

Practitioners should be cautious of recommending extreme diets due to potential health risks.

Average hemoglobin A1c value decreased from 5.8% to 5.6% in all patients (p < 0.001) and from 6.6% to 6.2% in patients with type 2 diabetes (p < 0.001).

Practitioners can expect improvements in glycemic control in patients participating in this program.

Weight loss following bariatric surgery reduced the risk of complications of TKA in people with BMI greater than or equal to 35.

Practitioners may consider recommending bariatric surgery for patients with severe obesity prior to TKA to reduce complication risks.

The between-group difference in BMI at 12 months was -6.32 in favor of the intervention group.

Practitioners can expect significant BMI reduction in patients undergoing bariatric surgery before TKA.

Metformin has the most evidence to support its use in targeting antipsychotic-induced weight gain.

Metformin should be considered as a treatment option for managing weight gain in these patients.

A model to prescribe exercise dose that considers various cardiovascular risk factors can improve individual outcomes from cardiac rehabilitation.

Practitioners should consider a comprehensive assessment of cardiovascular risk factors when prescribing exercise in cardiac rehabilitation.

Management of diabetic nephropathy requires a comprehensive treatment approach including lifestyle optimization and medication.

A multifaceted treatment plan is essential for managing diabetic nephropathy in T2D patients.

Patients can fully compensate for amino acid removal by ingesting ample protein during hemodialysis.

Encourage protein intake during hemodialysis to mitigate malnutrition.

Tirzepatide significantly increased fat oxidation while decreasing carbohydrate and protein oxidation rates.

Practitioners may leverage TZP's effects on fat oxidation to optimize weight loss protocols.