Browse the evidence

Obesity prevalence is projected to grow by 40% in the next decade.

Practitioners should prepare for increased obesity-related health issues in the coming decade.

The incidence of obesity-related glomerulopathy has increased tenfold in recent years.

Clinicians should be aware of the rising rates of kidney issues related to obesity.

Ninety-four percent of full service meals and seventy-two percent of fast food meals contained at least 600 kcal.

Practitioners should be aware that many restaurant meals are high in calories, impacting dietary recommendations.

The national penny-per-ounce sugar-sweetened beverage (SSB) tax was highly cost-saving from health care and societal perspectives.

Implementing an SSB tax could lead to significant cost savings in health care.

Incremental cost-effectiveness ratios for the SSB tax ranged from $20,247 to $42,662 per quality-adjusted life year for 100% price pass-through.

The SSB tax could be a cost-effective public health intervention.

The SSB tax positively affected both tax revenues and health care cost savings for the government.

The SSB tax could enhance government revenue while reducing health care costs.

The adjusted hazard ratios for the highest tertile of achieved plasma levels were 0.98 for EPA and 1.02 for DHA.

The lack of significant hazard ratios suggests that high levels of EPA and DHA do not alter cardiovascular risk in this population.

Late reoperation was significantly higher after gastric banding compared with gastric bypass (31.4% vs. 8.1%, P < 0.01).

Gastric banding may carry a higher risk of needing reoperation compared to gastric bypass.

Amino acids supplementation results are equivocal and are not warranted.

Athletes may not benefit from amino acid supplements as much as from protein supplements.

Plasma TMAO, carnitine, crotonobetaine, and γ-butyrobetaine concentrations were positively associated with fasting insulin level.

Higher levels of these metabolites may indicate increased fasting insulin levels, which could inform dietary or lifestyle interventions.

Training muscle groups 1 day per week vs. 2 days per week does not result in significant differences in maximal strength, muscle thickness, or muscle endurance in trained men after 8 weeks.

Both training frequencies can be effective for neuromuscular adaptations.

Training age was not a significant predictor of rating accuracy for RIR.

Coaches should not assume that more experienced lifters will have better RIR accuracy.

The food industry plays a significant role in funding nutrition research.

Practitioners should be aware of the influence of food industry funding on nutrition research.

The CDC has recommended actions to manage conflicts of interest in nutrition research.

Practitioners should consider CDC recommendations when evaluating nutrition research.

To achieve nondominance, the annual price of semaglutide would need to be reduced from $13,618 to $3,591.

This suggests that pricing strategies for semaglutide could significantly impact its adoption in clinical practice.

AM833 has a unique pharmacological profile across diverse measures of receptor binding, activation, and regulation.

Understanding AM833's unique profile can inform its therapeutic use.

Liraglutide has some common adverse effects, although generally not serious ones.

Practitioners should be aware of potential side effects when prescribing liraglutide.

Obesity has tripled in the last 10 years, killing approximately 28 million people each year.

Health practitioners should be aware of the growing obesity epidemic and its significant mortality impact.

Cardiomyocyte lipid aggregation in obesity causes insulin resistance and cardiovascular hypertrophy, reducing overall heart function.

Interventions targeting lipid metabolism may improve heart function in obese patients.

The review emphasizes moving from a binary approach to a quantitative approach in trials regarding glycaemic exposure.

Researchers should consider adopting quantitative measures of glycaemic exposure in future trials to better assess cardiovascular outcomes.

There was no overall pooled effect on HbA1c in favor of restricting carbohydrate.

Carbohydrate restriction may not significantly improve glycaemic control in Type 2 diabetes.

The implementation of MTMs could potentially lead to net cost savings of $13.6 billion annually from a health care perspective.

Expanding coverage for MTMs could be a financially beneficial policy for healthcare systems.

Choosing the optimal diet therapy for a patient with NAFLD is complicated due to the multifactorial nature of the disease.

Practitioners should recognize the complexity in selecting diet therapies for NAFLD patients.

The evidence for the benefits of power training on physical function and self-reported function was rated as low-certainty.

Practitioners should be aware of the limitations in the evidence when recommending power training.