Research
Cellular
Cardiomyocyte lipid aggregation in obesity causes insulin resistance and cardiovascular hypertrophy, reducing overall heart function.
Interventions targeting lipid metabolism may improve heart function in obese patients.
StrongSupportsmedium confidence
This cardiomyocyte lipid aggregation has been demonstrated to cause insulin resistance and cardiovascular hypertrophy, and to reduce the heart functions in general.
Why this rating
The claim is based on a review of existing literature.
Source
Obesity and its cardiovascular effects
Christian Ortega‐Loubon et al. · Diabetes/Metabolism Research and Reviews · 2019
DOI 10.1002/dmrr.3135
reviewCited 64×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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