Research
Molecular
The exact molecule(s) that ‘sense’ mechanical loading and translate that signal to a biochemical event leading to upregulation of MPS remains elusive.
Further research is needed to identify the molecules involved in sensing mechanical loading.
StrongQualifiesmedium confidence
However, the exact molecule(s) that ‘sense’ mechanical loading and translate that signal to a biochemical event leading to upregulation of MPS remains elusive.
Why this rating
The claim reflects ongoing research and knowledge gaps in the field.
Source
The influence of mechanical loading on skeletal muscle protein turnover
Amy J. Hector et al. · 2015
DOI 10.7457/cmep.v4i1
reviewCited 3×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Resistance exercise increases rates of muscle protein synthesis (MPS) in a mechanistic target of rapamycin complex 1 (mTORC1)-dependent manner.Strong
- Periods of unloading lead to a decrease in muscle protein synthesis (MPS) and potentially a transient increase in muscle protein breakdown (MPB).Strong
Related findings · Molecular
- QRISK decreased markedly after weight loss from 18.9 ± 2.2% to 11.2 ± 1.6%, p < 0.0001.Strong
- Normalization of 10-year cardiovascular risk and heart age is possible after substantial dietary weight loss and remission of T2DM.Strong
- The Low-Fat Plus diet resulted in a greater reduction in total cholesterol compared to the Low-Fat diet, with changes of -0.46 mmol/L (-17.6 mg/dL) versus -0.24 mmol/L (-9.2 mg/dL) respectively (P = 0.01).Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →