Research
Metabolic adaptation
Exenatide combined with Metformin improved 2-hour oral glucose tolerance test (OGTT) values by a mean difference of -1.78 (p < 0.001).
The combination therapy may enhance glucose tolerance in women with PCOS.
StrongSupportsmedium confidence
Combination therapy also improved 2-h OGTT values (MD: -1.78; p < 0.001).
Why this rating
Based on a systematic review and meta-analysis of five randomized controlled trials.
Source
Effects of Exenatide plus Metformin versus Metformin alone on insulin resistance in women with Polycystic Ovary Syndrome: A systematic review and meta‐analysis
Abd‐alrahman Al‐Qudah et al. · Journal of obstetrics and gynaecology research · 2025
Meta-analysisCited 2×
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