Research
Metabolic adaptation
Exenatide combined with Metformin reduced body mass index (BMI) by a mean difference of -0.4 (p = 0.03).
The combination therapy may assist in weight management for women with PCOS.
StrongSupportsmedium confidence
Combination therapy also reduced BMI (MD: -0.4; p = 0.03).
Why this rating
Based on a systematic review and meta-analysis of five randomized controlled trials.
Source
Effects of Exenatide plus Metformin versus Metformin alone on insulin resistance in women with Polycystic Ovary Syndrome: A systematic review and meta‐analysis
Abd‐alrahman Al‐Qudah et al. · Journal of obstetrics and gynaecology research · 2025
Meta-analysisCited 2×
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