Research
Cellular
Obesity initiates the development of insulin resistance through increased adipose tissue size, inflammation, and ectopic fat deposition.
Understanding the role of obesity in insulin resistance can guide interventions.
StrongSupportsmedium confidence
Obesity is one of the main factors initiating the development of insulin resistance through increased adipose tissue size, inflammation, and ectopic fat deposition in insulin-sensitive tissues.
Why this rating
The abstract presents a comprehensive overview of the mechanisms involved.
Source
Targeting the root cause of obesity-related comorbidities through weight independent and dependent actions on insulin sensitivity: Benefits of dual amylin and calcitonin receptor agonists
Anna Thorsø Larsen et al. · Biomedicine & Pharmacotherapy · 2025
DOI 10.1016/j.biopha.2025.118388
reviewCited 1×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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