Research
Molecular
iWAT injection of MPDA@TZP improved leptin resistance, beiging, lipid metabolism, mitochondrial activity, and branched-chain amino acid (BCAA) catabolism in iWAT.
Understanding these metabolic improvements can guide targeted therapies for obesity.
StrongSupportsmedium confidence
Transcriptomic analysis indicated that iWAT injection of MPDA@TZP improved leptin resistance, beiging, lipid metabolism, mitochondrial activity and branched-chain amino acid (BCAA) catabolism in iWAT.
Why this rating
Based on the detailed transcriptomic analysis conducted in the study.
Source
Tirzepatide retention in iWAT with mesoporous polydopamine encapsulation enhances weight loss through leptin receptor signaling
Lin Mi et al. · Journal of Advanced Research · 2025
otherCited 1×
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