Research
Cellular
MPDA@TZP increased the retention time of TZP in the iWAT of mice and had a more dramatic effect on weight loss and improvement in plasma lipid profiles compared to TZP alone in DIO mice.
Encapsulating tirzepatide may enhance its effectiveness for weight loss in specific adipose tissues.
StrongSupportsmedium confidence
MPDA@TZP successfully increased the retention time of TZP in the iWAT of mice and had a more dramatic effect on weight loss and improvement in plasma lipid profiles compared to TZP alone in DIO mice.
Why this rating
Based on the study design involving animal models and specific interventions.
Source
Tirzepatide retention in iWAT with mesoporous polydopamine encapsulation enhances weight loss through leptin receptor signaling
Lin Mi et al. · Journal of Advanced Research · 2025
DOI 10.1016/j.jare.2025.09.009
otherCited 1×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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