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Resistance training with a 7-9 RPE may elicit marginally greater acute responses of CK and LDH than 4-6 RPE over time.
Practitioners may consider incorporating higher RPE levels to enhance muscle damage responses.
StrongSupportsmedium confidence
Our findings indicate that resistance training with a 7-9 RPE may elicit marginally greater acute responses of CK and LDH than 4-6 RPE over time.
Why this rating
Based on study design from abstract.
Source
Effect Of Proximity To Failure During Resistance Training On Longitudinal Markers Of Muscle Damage
David Castro‐Díaz et al. · Medicine & Science in Sports & Exercise · 2023
DOI 10.1249/01.mss.0000984808.46637.7f
rct · n=19
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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