Research
Metabolic adaptation
DNL fatty acid levels decrease on a low-carbohydrate (LC) diet and do not change on a low-fat (LF) diet.
Low-carbohydrate diets may be beneficial for reducing certain fatty acids associated with insulin resistance.
StrongSupportsmedium confidence
16:1n7 decreased on the LC diet and did not change on the LF diet (LC: -0.5% [-0.7, -0.3] vs LF: -0.1% [-0.3, 0.2]).
Why this rating
Based on the study design involving dietary interventions.
Source
Abstract P220: Elevated De Novo Lipogenesis Fatty Acids and Lower Omega-6 Fatty Acids Are Associated With Markers of Insulin Resistance and Respond to Changes in Dietary Carbohydrate Intake in Overweight Individuals on Weight Loss Diets
Kristina Harris Jackson et al. · Circulation · 2018
cohort · n=61
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