Research
Metabolic adaptation
Significant reductions were observed in waist circumference (MD -9.40; 95% CI: -11.91 to -6.89).
Incretin polyagonists may help reduce waist circumference in obese individuals.
StrongSupportsmedium confidence
Significant reductions were also observed in waist circumference (MD -9.40; 95% CI: -11.91 to -6.89).
Why this rating
Based on a systematic review and meta-analysis of randomized controlled trials.
Source
Incretin-Based Dual and Triple Agonists in Overweight or Obese Individuals: A Systematic Review and Meta-Analysis
Zhi Hong Chan et al. · Cardiology in Review · 2026
Meta-analysis
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