Research
Metabolic adaptation
Obesity is associated with increased risk of heart failure (HF), with a 63% increase in men and a 69% increase in women compared to those with normal BMI.
Practitioners should be aware of the significant risk of heart failure in obese patients, regardless of metabolic health.
StrongSupportsmedium confidence
Obesity without metabolic abnormality increases the risk of HF by 63% and 69%, compared to those with normal BMI.
Why this rating
Based on study design from abstract.
Source
Obesity, metabolic health status, and adverse outcomes in men and women
R. Ananda et al. · American Journal of Preventive Cardiology · 2026
DOI 10.1016/j.ajpc.2026.101556
cohort · n=157159
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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