Research
Metabolic adaptation
The presence of metabolic abnormalities doubles event rates associated with obesity, with risk increasing with the number of metabolic abnormalities present.
Practitioners should consider the presence of metabolic abnormalities when assessing the risks of obesity in patients.
StrongSupportsmedium confidence
The presence of metabolic abnormality doubles event-rates associated with obesity, with risk increasing with number of metabolic-abnormalities present.
Why this rating
Based on study design from abstract.
Source
Obesity, metabolic health status, and adverse outcomes in men and women
R. Ananda et al. · American Journal of Preventive Cardiology · 2026
DOI 10.1016/j.ajpc.2026.101556
cohort · n=157159
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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