Research
Cellular
KN069 was well tolerated, with predominantly mild-to-moderate gastrointestinal adverse events.
KN069 may be a safe option for weight management in this population.
StrongSupportsmedium confidence
KN069 was well tolerated, with predominantly mild-to-moderate gastrointestinal adverse events.
Why this rating
Based on the randomized, double-blind trial design.
Source
A Phase 1, Randomised, Double‐Blind, Placebo‐Controlled Trial Investigating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of <scp>KN069</scp> (a Dual <scp>GLP</scp> ‐ <scp>1R</scp> Agonist and <scp>GIPR</scp> Antagonist) in Male Adults With Overweight or Obesity
Jinlian Xie et al. · Diabetes Obesity and Metabolism · 2026
DOI 10.1111/dom.70794
rct · n=48
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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