Research

Cellular

Epicardial adipose tissue may contribute to arrhythmogenesis through pro-inflammatory and pro-fibrotic effects.

Addressing epicardial adipose tissue may be important in managing arrhythmias in obese patients.

StrongSupportsmedium confidence
Among the key mediators linking obesity to arrhythmogenesis, epicardial adipose tissue has emerged as a relevant factor that may contribute to local pro-inflammatory, pro-fibrotic, and autonomic effects on the myocardium.
Fulvio Cacciapuoti et al. · Life · 2026

Why this rating

The claim is based on established mechanisms linking obesity to arrhythmias.

Source

The Obesity–OSA–Arrhythmia Axis: Pathophysiological Mechanisms and Translational Therapeutic Targets

Fulvio Cacciapuoti et al. · Life · 2026

DOI 10.3390/life16050737

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DOI resolved against Crossref · corpus check 2026-06-10

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