Research
Cellular
In insulin resistance, endothelin-1 is directly involved in regulating muscle glucose uptake.
Understanding the role of ET-1 may help in developing targeted therapies for insulin resistance.
StrongSupportsmedium confidence
The finding supports that endogenous ET-1 is important in regulating muscle glucose uptake in IR.
Why this rating
Based on the study design involving human subjects and direct measurements.
Source
Factors potentially influencing pathogenetic mechanisms and hyperglycemia in pre-diabetes and type 2 diabetes : clinical studies in humans
Henrik Wagner · Figshare · 2016
other · n=48
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