Research
Cellular
Epicardial adipose tissue (EAT) may contribute to the pathophysiology observed in HFpEF.
Understanding the role of EAT may help in developing targeted therapies for HFpEF.
StrongQualifiesmedium confidence
Small poorly differentiated adipocytes with altered lipid:water content are associated with a proinflammatory secretome and may contribute to the pathophysiology observed in HFpEF.
Why this rating
The claim is based on established research linking EAT to heart failure.
Source
Epicardial adipose tissue in obesity-related cardiac dysfunction
Sarah L Ayton et al. · Heart · 2021
DOI 10.1136/heartjnl-2020-318242
otherCited 46×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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