Research
Cellular
Eccentric contraction-induced Z-band disruption is approximately 14-fold greater than typically observed in resting biopsies.
Practitioners should note that eccentric contractions can cause significant muscle damage.
StrongSupportsmedium confidence
Biopsies at all three sites showed Z-band disruption, much greater (i.e., approximately 14-fold) than is typically observed in resting biopsies.
Why this rating
Based on the study design involving multiple biopsies and a defined protocol.
Source
Variability in Estimating Eccentric Contraction-Induced Muscle Damage and Inflammation in Humans
Louise J. Beaton et al. · Canadian Journal of Applied Physiology · 2002
DOI 10.1139/h02-028
other · n=5Cited 37×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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