Research
Cellular
The Open Formulary group had a mean reduction in A1c of −2.7 ± 2.4, which was significantly greater than the Restrictive Formulary group's reduction of −0.74 ± 2.1.
Practitioners may consider that an open formulary can lead to better glycemic control in patients with type 2 diabetes.
StrongSupportsmedium confidence
While both the Restrictive and Open Formulary groups had significant reductions in mean A1c from a baseline of −0.74 ± 2.1 ( p = 0.02) and − 2.7 ± 2.4 ( p < 0.001), respectively, the magnitude of A1c reduction was greater in the Open group ( p < 0.001).
Why this rating
The study is a retrospective cohort study with clear outcomes.
Source
Impact of a Restrictive Formulary on glycemic control compared with an Open Formulary
Tinh Duong et al. · JACCP JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY · 2024
DOI 10.1002/jac5.2048
cohort
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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