Mixed
In patients with type 2 diabetes and recent acute coronary syndrome, a body weight gain of 5% or more is independently associated with an increased risk of cardiovascular mortality or heart failure hospitalization.
If you have diabetes and heart disease, gaining more than 5% of your body weight is a warning sign of heart failure. It likely means your body is holding onto fluid. Monitor your weight daily and seek medical attention if you see a rapid increase, as this may require medication adjustment for your heart.
A weight gain ≥ 5% was independently associated with an increase in the risk of subsequent cardiovascular mortality or heart failure hospitalization: adjusted HR (95% CI) 1.34 (1.02–1.76), P = 0.033.
Why this rating
Derived from the same large RCT (EXAMINE) with time-updated Cox models.
Source
Body weight changes in patients with type 2 diabetes and a recent acute coronary syndrome: an analysis from the EXAMINE trial
João Pedro Ferreira et al. · Cardiovascular Diabetology · 2021
DOI 10.1186/s12933-021-01382-8
More from this paper
- In patients with type 2 diabetes and recent acute coronary syndrome, a body weight loss of 5% or more is independently associated with a significantly higher risk of all-cause mortality and cardiovascular events.Good
- In patients with type 2 diabetes and recent acute coronary syndrome, a higher baseline Body Mass Index (BMI > 30 kg/m2) is associated with a lower risk of primary cardiovascular outcomes compared to those with a BMI of 26-30 kg/m2.Good
Related findings · Mixed
- Bariatric surgery (VSG and RYGB) is the most effective and sustainable treatment for obesity, producing marked and sustained weight loss that non-surgical interventions cannot match.Strong
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- For patients with Class III obesity (BMI >39.9 kg/m2), metabolic bariatric surgery (MBS) is significantly more effective than any currently approved medication, with BilioPancreatic Diversion (BPD) showing the highest estimated weight loss.Strong
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