Mixed
Circulating levels of trans-16:1n9 and total trans-18:1 are not significantly associated with total mortality or cardiovascular disease mortality in older adults.
You do not need to avoid natural sources of trans fats (like those found in dairy and meat) which contain t-16:1n9 and t-18:1, as this study found no link to increased mortality or heart disease risk. Focus your efforts on avoiding industrial trans fats (partially hydrogenated oils) instead.
Neither t-16:1n9 nor t-18:1 was significantly associated with total mortality or CVD... No other TFAs were significantly related to CVD or non-CVD mortality.
Why this rating
Robust cohort design, but the finding is a null result for common subtypes.
Source
Plasma Phospholipid <i>Trans</i> ‐Fatty Acids Levels, Cardiovascular Diseases, and Total Mortality: The Cardiovascular Health Study
Qianyi Wang et al. · Journal of the American Heart Association · 2014
DOI 10.1161/jaha.114.000914
More from this paper
- Higher circulating levels of the trans-fatty acid isomer trans/trans-18:2 (t/t-18:2) are associated with significantly increased risks of total mortality, cardiovascular disease (CVD) mortality, and total coronary heart disease (CHD).Good
- Higher circulating levels of the trans-fatty acid isomer trans/cis-18:2 (t/c-18:2) are associated with increased total mortality and coronary heart disease (CHD) incidence, but only after mutual adjustment for other TFA subtypes.Good
Related findings · Mixed
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