Energy balance
In adults with type 2 diabetes, behavioral weight loss interventions do not significantly reduce the long-term risk of cardiovascular disease events or all-cause mortality compared to standard care.
For people with type 2 diabetes, relying solely on behavioral weight loss interventions (diet and exercise) may not be enough to prevent cardiovascular disease or death in the long term. While weight loss is still recommended for other benefits like diabetes remission, patients should discuss comprehensive cardiovascular risk management, including medications with proven cardiovascular benefits, with their healthcare provider.
Behavioural interventions targeting weight loss showed no effect on CVD events (pooled HR [95% CI] 0.95 [0.71, 1.27]; I2 = 50.1%).
Why this rating
Based on a systematic review and meta-analysis of 3 RCTs and 14 observational studies, though with moderate heterogeneity and risk of bias in observational studies.
Source
Effects of Weight Loss and Interaction with Physical Activity on Risks of Cardiovascular Outcomes in Individuals with Type 2 Diabetes
Claudia R.L. Cardoso et al. · Endocrinology and Metabolism · 2023
DOI 10.3803/enm.2023.1690
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