Energy balance
Unintentional weight loss in type 2 diabetes is associated with a higher risk of all-cause mortality, whereas the association with intentional weight loss is unclear.
Unintentional weight loss in type 2 diabetes should be taken seriously as it may signal underlying health issues and is linked to higher mortality. The impact of intentional weight loss on mortality is less clear, so patients should focus on overall health management rather than just weight loss.
Unintentional weight loss (vs no change) was associated with higher risks of all-cause mortality, but associations with intentional weight loss were unclear.
Why this rating
Based on observational studies with mixed results and high risk of bias in some.
Source
Effects of Weight Loss and Interaction with Physical Activity on Risks of Cardiovascular Outcomes in Individuals with Type 2 Diabetes
Claudia R.L. Cardoso et al. · Endocrinology and Metabolism · 2023
DOI 10.3803/enm.2023.1690
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