Mixed
Central adiposity (high waist circumference) is a significant independent risk factor for incident cardiovascular disease and all-cause mortality in individuals with normal glucose tolerance (NGT).
If you have normal blood sugar, don't ignore your waist size. High waist circumference significantly increases your risk of heart disease and death, even if your glucose levels are normal. Focus on reducing waist circumference through diet and exercise.
Regarding central adiposity, multivariate analysis revealed that elevated WC in NGT participants is associated with incident CVD [1.27(1.12–1.46)] and all-cause mortality [1.13 (1.00–1.28)].
Why this rating
Large pooled cohort, long follow-up, multivariable adjusted, observational.
Source
The impact of obesity on different glucose tolerance status with incident cardiovascular disease and mortality events over 15 years of follow-up: a pooled cohort analysis
Samaneh Asgari et al. · Diabetology & Metabolic Syndrome · 2024
DOI 10.1186/s13098-023-01253-0
More from this paper
- General obesity (BMI ≥ 30 kg/m²) significantly increases the risk of cardiovascular and all-cause mortality across all glucose tolerance statuses (normoglycemia, pre-diabetes, and type 2 diabetes), regardless of glycemic control.Good
- General obesity does not significantly increase the risk of incident cardiovascular disease (CVD) events in individuals with type 2 diabetes, although it does increase mortality risk.Moderate
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