Research
Mixed
Higher genetically predicted BMI does not increase the risk of cancer mortality.
While higher BMI increases risks for other causes of death, this study did not find a link to cancer mortality.
GoodRefutesMEDIUM confidence
it was not positively related to cancer (HR 0.85, 95% CI 0.67–1.09), overall or for specific sites.
Why this rating
Strong MR design, but the confidence interval includes 1.0, indicating no statistically significant positive association.
Source
A Mendelian randomization study of the effect of body mass index on 52 causes of death among 125 000 Mexican adults with admixed ancestry
Louisa Gnatiuc et al. · International Journal of Epidemiology · 2025
DOI 10.1093/ije/dyaf110
cohort · n=125003Cited 2×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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