Research
Energy balance
Caffeine (375 mg capsule or equivalent from coffee/tea) increases energy expenditure and brown adipose tissue activity in physically active humans.
Consume 375 mg of caffeine (or equivalent from coffee/tea) 30 minutes before activity. This has been shown to increase energy expenditure and activate brown fat, particularly in physically active men. It is a practical way to leverage a common substance for metabolic benefit.
GoodSupportsHIGH confidence
Physically active men with high brown adipose tissue activity showed increased energy expenditure after caffeine supplementation (375 mg vs. placebo) 30 min before data collection. BAT activation (temperature ROI) increased
Why this rating
Supported by human clinical studies using infrared thermography and PET-CT.
Source
The impact of dietary factors on the function of brown and beige adipose tissues—implications on health and disease
Bruna Bombassaro et al. · Frontiers in Nutrition · 2025
DOI 10.3389/fnut.2025.1626068
narrative_reviewCited 1×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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