Research
Energy balance
Obesity is the most important modifiable risk factor for Type 2 Diabetes, influencing insulin resistance and disease progression.
Obesity is the single most important risk factor for developing Type 2 Diabetes, affecting nearly 90% of diabetic patients. Excess body weight directly contributes to insulin resistance. Managing body weight is therefore the most critical modifiable factor in preventing and managing T2DM.
StrongSupportsHIGH confidence
Substantial epidemiological studies have shown that obesity is the most important risk factor for T2DM, which may influence the development of insulin resistance and disease progression [42]. Nearly 90% of diabetic patients develop T2DM mostly relating to excess body weight according to the World Health Organization (WHO, 2011).
Why this rating
Supported by substantial epidemiological studies and WHO data.
Source
Risk Factors Contributing to Type 2 Diabetes and Recent Advances in the Treatment and Prevention
Yanling Wu et al. · International Journal of Medical Sciences · 2014
DOI 10.7150/ijms.10001
narrative_reviewCited 1,275×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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