Research
Micronutrients & recovery
Among women who have had a myocardial infarction, low-dose ALA supplementation (2g/day) may reduce the rate of major cardiovascular events, approaching statistical significance.
For women who have had a heart attack, taking 2g of ALA (plant-based n-3) daily might offer some protection against future cardiovascular events, although the evidence is not definitive. This should not replace standard medical care.
GoodQualifiesMEDIUM confidence
In the prespecified subgroup of women, ALA, as compared with placebo and EPA–DHA alone, was associated with a reduction in the rate of major cardiovascular events that approached significance (hazard ratio, 0.73; 95% CI, 0.51 to 1.03; P = 0.07).
Why this rating
Based on a pre-specified subgroup analysis of a high-quality RCT, but the result did not reach statistical significance (P=0.07).
Source
n–3 Fatty Acids and Cardiovascular Events after Myocardial Infarction
Daan Kromhout et al. · New England Journal of Medicine · 2010
DOI 10.1056/nejmoa1003603
rct · n=4837Cited 927×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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