Research
Micronutrients & recovery
In diabetic patients who have had a myocardial infarction, EPA-DHA supplementation may reduce the rate of fatal coronary heart disease.
For diabetic patients who have had a heart attack, taking EPA-DHA supplements might significantly reduce the risk of fatal coronary heart disease, based on exploratory analysis. However, this finding requires confirmation in dedicated studies and should not replace standard medical care.
ModerateQualifiesLOW confidence
A post hoc, exploratory analysis of data from these diabetic patients showed that the rates of fatal coronary heart disease and arrhythmia-related events were lower among patients in the EPA–DHA groups than among those in the groups that received no EPA–DHA (hazard ratio for fatal coronary heart disease, 0.51; 95% CI, 0.27 to 0.97; P = 0.04).
Why this rating
Based on a post-hoc subgroup analysis of a secondary endpoint, which is prone to false positives and requires validation.
Source
n–3 Fatty Acids and Cardiovascular Events after Myocardial Infarction
Daan Kromhout et al. · New England Journal of Medicine · 2010
rct · n=4837Cited 927×
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