Research

Micronutrients & recovery

Increasing dietary intake of omega-3 long-chain polyunsaturated fatty acids (LC-PUFAs) and maintaining an omega-6/omega-3 ratio of 2–4:1 is associated with a reduced risk of breast, prostate, colon, and renal cancers.

To support cancer prevention and overall health, aim to consume 2-3 servings of oily fish weekly to get 200-500 mg of EPA/DHA daily. If you have existing cardiovascular risks, medical guidance may suggest 1-4 grams daily. Crucially, try to lower your omega-6 to omega-3 ratio from the typical Western 20:1 down to 2-4:1 by reducing processed seed oils and increasing omega-3 sources.

ModerateSupportsMEDIUM confidence
Recent findings reviewed in the present study highlight that the omega-6 fatty acid ARA appears increased, and omega-3 EPA and DHA decreased in most cancer tissues compared to normal ones, and that increments in omega-3 LC-PUFAs consumption and an omega-6/omega-3 ratio of 2–4:1, are associated with a reduced risk of breast, prostate, colon and renal cancers.
Rafael Zárate et al. · Clinical and Translational Medicine · 2017

Why this rating

The paper is a review summarizing observational and clinical data; it notes mixed results in recent trials for other conditions, suggesting moderate certainty for cancer specifically based on ratio associations.

Source

Significance of long chain polyunsaturated fatty acids in human health

Rafael Zárate et al. · Clinical and Translational Medicine · 2017

narrative_reviewCited 545×
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