Research

Micronutrients & recovery

CoQ10 supplementation (100-300 mg/day) improves mitochondrial function and reduces cardiovascular mortality in elderly populations with low baseline CoQ10 levels, particularly when combined with selenium.

If you are elderly and have low CoQ10 levels, supplementation with 200mg CoQ10 daily, potentially combined with 200mcg of selenium, may significantly reduce your risk of cardiovascular death over the long term. Consult a doctor to check your baseline levels before starting.

GoodSupportsHIGH confidence
A study on the effects of long-term treatment with CoQ10 (200 mg/day) plus selenium (200 µg as selenized yeast) in a homogeneous Swedish healthy elderly population (n = 219) revealed a significant reduction in cardiovascular mortality not only during the 4-year treatment period, but also 10 years later, compared to those taking either a placebo (n = 222) or were without treatment (n = 227) (Alehagen et al., 2015, 2016).
Juan Diego Hernández‐Camacho et al. · Frontiers in Physiology · 2018

Why this rating

Based on a randomized, controlled trial with long-term follow-up, though the paper notes general limitations in trial consistency.

Source

Coenzyme Q10 Supplementation in Aging and Disease

Juan Diego Hernández‐Camacho et al. · Frontiers in Physiology · 2018

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