Research
Micronutrients & recovery
CoQ10 supplementation (100-300 mg/day) reduces inflammatory markers (TNF-α, IL-6) in patients with metabolic diseases, rheumatoid arthritis, and other inflammatory conditions.
If you have chronic inflammation, metabolic syndrome, or rheumatoid arthritis, taking 60-500mg of CoQ10 daily may help lower inflammatory markers like TNF-α and IL-6. This is particularly relevant if you have low baseline CoQ10 levels.
GoodSupportsHIGH confidence
Administration of CoQ10 in doses ranging from 60 to 500 mg/day for a 1-week to 4-month intervention period significantly decreased production of inflammatory cytokines. The authors also surmised that CoQ10 supplementation decreased pro-inflammatory cytokines and inflammatory markers in the elderly with low CoQ10 levels (Fan et al., 2017).
Why this rating
Based on meta-analyses and multiple RCTs, though the paper notes inconsistencies in trial designs.
Source
Coenzyme Q10 Supplementation in Aging and Disease
Juan Diego Hernández‐Camacho et al. · Frontiers in Physiology · 2018
narrative_reviewCited 351×
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