Research
Micronutrients & recovery
CoQ10 supplementation (2400 mg/day) is safe and well-tolerated in patients with early-stage Huntington's disease, but does not slow functional decline.
If you or a family member has early-stage Huntington's disease, high-dose CoQ10 (2400mg/day) is safe but has not been shown to slow the disease's progression. Do not rely on it as a treatment for slowing decline.
GoodRefutesHIGH confidence
a more recent multicenter randomized, double-blind, and placebo-controlled trial with CoQ10 in 609 patients with early-stage Huntington’s disease did not slow the rate of patients’ functional decline (McGarry et al., 2017). There is not enough evidence to indicate that CoQ10 supplementation can delay the progression of Huntington’s disease, at least in its early stages.
Why this rating
Based on a large, multicenter RCT.
Source
Coenzyme Q10 Supplementation in Aging and Disease
Juan Diego Hernández‐Camacho et al. · Frontiers in Physiology · 2018
narrative_reviewCited 351×
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