Research
Mixed
Aging is a multifactorial biological process driven by interconnected molecular changes across genomics, epigenomics, transcriptomics, proteomics, and metabolomics, which can be mapped and potentially intervened upon through multi-omics analysis.
This paper does not provide a specific user protocol. It establishes that aging is a complex, multi-layered biological process involving genes, proteins, and metabolism, and that scientific databases exist to track these changes across species to develop interventions.
ModerateSupportsMEDIUM confidence
Organismal aging is driven by interconnected molecular changes encompassing internal and extracellular factors. Combinational analysis of high-throughput ‘multi-omics’ datasets... can provide a multi-dimensional, integrated profile of the heterogeneous aging process... facilitate the development of new aging interventions.
Why this rating
This is a database resource paper describing existing data curation, not a primary experimental study with new causal evidence.
Source
Aging Atlas: a multi-omics database for aging biology
Guang‐Hui Liu et al. · Nucleic Acids Research · 2020
DOI 10.1093/nar/gkaa894
narrative_reviewCited 337×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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