Research
Micronutrients & recovery
Geroprotective compounds (drugs) alter gene expression and regulation, providing a mechanism for lifespan and healthspan extension.
There are specific drugs (geroprotectors) that change gene expression to potentially extend healthspan. This database catalogs these drugs and their effects, helping researchers find potential treatments.
ModerateSupportsMEDIUM confidence
This geroprotective compounds module focuses on geroprotectors... revealing changes in gene expression caused by specific lifespan/healthspan-extending drugs.
Why this rating
The paper describes a database of such compounds, citing literature, but does not present new primary experimental data.
Source
Aging Atlas: a multi-omics database for aging biology
Guang‐Hui Liu et al. · Nucleic Acids Research · 2020
DOI 10.1093/nar/gkaa894
narrative_reviewCited 337×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Caloric restriction (CR) reprograms the single-cell transcriptional landscape of aging, altering gene expression patterns in specific tissues.Good
- Aging is a multifactorial biological process driven by interconnected molecular changes across genomics, epigenomics, transcriptomics, proteomics, and metabolomics, which can be mapped and potentially intervened upon through multi-omics analysis.Moderate
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