Research
Mixed
Resistance exercise training increases the proportion of endothelial cells and pericytes in human skeletal muscle, while acute resistance exercise increases the proportion of neutrophils.
To improve muscle vascularization and immune readiness, engage in consistent resistance training (3x/week). Expect an immediate, short-term spike in neutrophils after each session, but focus on the long-term benefit of increased endothelial and pericyte presence which supports muscle health and recovery.
GoodSupportsHIGH confidence
We found an increase in the endothelial/pericyte compartment due to exercise training, an increase in neutrophils in response to acute exercise, and a difference in lymphocyte proportion that is mediated by both age and gender.
Why this rating
Based on computational deconvolution of a large, well-characterized public dataset (n=110) with validation against fiber-type proportions.
Source
Single-cell transcriptional profiles in human skeletal muscle
Aliza B. Rubenstein et al. · Scientific Reports · 2020
DOI 10.1038/s41598-019-57110-6
mechanism_onlyCited 336×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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