Research
Mixed
Obstructive Sleep Apnea (OSA) is independently associated with glucose intolerance and insulin resistance, but OSA at baseline does not significantly predict the development of diabetes after adjusting for obesity.
Diagnose and treat OSA for cardiovascular and sleep quality benefits, but do not expect CPAP alone to resolve insulin resistance or diabetes in obese patients. Focus on weight management and lifestyle interventions for metabolic control.
ModerateQualifiesMEDIUM confidence
In the general population, obstructive sleep apnoea (OSA) is associated with glucose intolerance. OSA severity is also associated with the degree of IR. However, OSA at baseline does not seem to significantly predict the development of diabetes.
Why this rating
Based on cross-sectional and longitudinal population studies with confounding factors.
Source
Sleep, sleep-disordered breathing and metabolic consequences
Patrick Lévy et al. · European Respiratory Journal · 2009
DOI 10.1183/09031936.00166808
narrative_reviewCited 335×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Experimental sleep restriction causes insulin resistance and metabolic dysregulation in healthy subjects via increased evening cortisol, sympathetic activation, and altered appetite hormones (leptin/ghrelin).Good
- Continuous Positive Airway Pressure (CPAP) treatment improves glucose metabolism in non-diabetic and non-obese OSA patients, but has limited effect on glucose metabolism in obese OSA patients.Good
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