Micronutrients & recovery
Methionine restriction (MetR) extends lifespan across multiple species, including yeast, worms, flies, and mammals, by modulating methionine metabolism pathways and methyltransferase activity.
Restricting dietary methionine has been shown to extend lifespan in various model organisms. This involves reducing intake of methionine-rich foods. The exact mechanism involves modulating methionine metabolism and methyltransferase activity, potentially through reducing translation rates, modifying gene expression, or inducing hormetic responses.
Methionine restriction (MetR) extends lifespan across different species and exerts beneficial effects on metabolic health and inflammatory responses.
Why this rating
Supported by multiple studies across yeast, worms, flies, and mammals, though exact mechanisms vary.
Source
Methionine metabolism and methyltransferases in the regulation of aging and lifespan extension across species
Andrey A. Parkhitko et al. · Aging Cell · 2019
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