Research
Micronutrients & recovery
Adherence to a Western diet (high in refined carbohydrates, simple sugars, and saturated fats) causes intestinal dysbiosis, which triggers oxidative stress and inflammatory cascades leading to Inflammatory Bowel Diseases (IBD).
To protect your gut health and reduce IBD risk, minimize intake of refined sugars, simple carbs, and saturated fats. These components drive dysbiosis and inflammation. Focus on whole foods to support a healthy microbiome.
ModerateSupportsMEDIUM confidence
The 'western diet', in particular a low - fiber high fat/high carbohydrate diet is one factor that can lead to severe dysbiosis... Several studies have shown a correlation between increased oxidative stress and a Western-style diet rich in fats and refined sugars. These products in fact, if taken frequently and in large quantities, cause an increase of the inflammatory state with ROS production and subsequent amplification of the inflammatory cascade
Why this rating
The paper is a literature review summarizing observational and animal studies; it lacks a single large-scale RCT.
Source
Nutrition, oxidative stress and intestinal dysbiosis: Influence of diet on gut microbiota in inflammatory bowel diseases
Giovanni Tomasello et al. · Biomedical Papers · 2016
DOI 10.5507/bp.2016.052
narrative_reviewCited 233×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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- Butyric acid (a short-chain fatty acid produced by bacterial fermentation of fiber) has anti-inflammatory effects and strengthens the intestinal barrier by increasing mucin production and tight junction proteins.Good
- Adherence to a Mediterranean or Vegetarian diet (rich in fiber, fruits, vegetables, olive oil, and fish) prevents dysbiosis and reduces the risk of Inflammatory Bowel Diseases (IBD).Moderate
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