Research
Micronutrients & recovery
Butyric acid (a short-chain fatty acid produced by bacterial fermentation of fiber) has anti-inflammatory effects and strengthens the intestinal barrier by increasing mucin production and tight junction proteins.
Consume adequate dietary fiber to allow gut bacteria to produce butyric acid. This strengthens your gut lining and reduces inflammation.
GoodSupportsHIGH confidence
Butyric acid has an important anti-inflammatory effect and controls the proliferation, differentiation and apoptosis of colonocytes. In addition, it strengthens the defensive barrier of the colon by increasing the production of mucin and antimicrobial peptides and by decreasing the intestinal epithelial permeability and increasing the expression of tight junction’s proteins
Why this rating
Supported by multiple references (5, 11, 15) within the review, indicating strong consensus on this mechanism.
Source
Nutrition, oxidative stress and intestinal dysbiosis: Influence of diet on gut microbiota in inflammatory bowel diseases
Giovanni Tomasello et al. · Biomedical Papers · 2016
DOI 10.5507/bp.2016.052
narrative_reviewCited 233×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Adherence to a Western diet (high in refined carbohydrates, simple sugars, and saturated fats) causes intestinal dysbiosis, which triggers oxidative stress and inflammatory cascades leading to Inflammatory Bowel Diseases (IBD).Moderate
- Adherence to a Mediterranean or Vegetarian diet (rich in fiber, fruits, vegetables, olive oil, and fish) prevents dysbiosis and reduces the risk of Inflammatory Bowel Diseases (IBD).Moderate
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