Mixed
Infant formula milk contains significantly higher levels of Advanced Glycation End Products (AGEs), specifically CML, compared to breast milk, potentially predisposing infants to inflammation and metabolic issues.
If using infant formula, be aware that processing creates AGEs. Follow preparation instructions carefully to avoid excessive heating. If breastfeeding is possible, it provides lower AGE exposure. For formula-fed infants, this is a known physiological factor contributing to early inflammatory load.
Formula milk is a rich source of primary adducts, such as carboxy-methyl lysine, which render an infant prone to inflammation, dementia, food allergies, and other diseases.
Why this rating
The paper cites studies showing high CML levels in formula but does not provide long-term human outcome data linking this directly to disease onset in infants, relying on mechanistic and biomarker evidence.
Source
Advanced Glycation End Products (AGEs) May Be a Striking Link Between Modern Diet and Health
Vidhu Gill et al. · Biomolecules · 2019
DOI 10.3390/biom9120888
More from this paper
- Consumption of high-temperature cooked foods (grilled, fried, baked) significantly increases systemic Advanced Glycation End Products (AGEs), which promotes oxidative stress, inflammation, and endocrine disruption, particularly in women with PCOS.Moderate
- Vitamin D3 supplementation can attenuate the negative effects of AGEs in women with PCOS by down-regulating the AGE-RAGE interaction and supporting steroidogenesis.Moderate
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