Mixed
High initial alpha diversity, female sex, high household income, and preserved exocrine pancreatic function are associated with the greatest stability of the faecal microbiota over a 5-year period.
Maintaining high microbial diversity and pancreatic health may help keep your gut microbiome stable. While you cannot change your sex or income, focusing on metabolic health and avoiding factors that reduce diversity (like unnecessary antibiotics) may support stability.
Greatest stability of the microbiome was determined by higher initial alpha diversity, female sex, high household income and preserved exocrine pancreatic function.
Why this rating
Large longitudinal cohort with robust statistical analysis controlling for confounders.
Source
Long-term instability of the intestinal microbiome is associated with metabolic liver disease, low microbiota diversity, diabetes mellitus and impaired exocrine pancreatic function
Fabian Frost et al. · Gut · 2020
DOI 10.1136/gutjnl-2020-322753
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- Long-term instability of the intestinal microbiome is significantly associated with metabolic liver disease (FLD) and diabetes mellitus, characterized by an increase in facultative pathogens like Enterobacteriaceae and Escherichia/Shigella.Good
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