Research
Mixed
A personalized dietary program favorably shifts gut microbiome composition, increasing the relative abundance of species associated with favorable cardiometabolic health, compared to standard dietary advice.
A personalized diet that considers your biological response to food may be more effective at improving your gut microbiome composition, specifically by increasing beneficial species, compared to standard dietary guidelines.
GoodSupportsMEDIUM confidence
Notably, among the 15 favorable species, we found eight species in the PDP group showing an increase in terms of relative abundance at the endpoint... conversely, in the control group, none of the 15 favorable species showed an increased relative abundance at the endpoint
Why this rating
RCT with microbiome analysis, but observational nature of microbiome-health association.
Source
Effects of a personalized nutrition program on cardiometabolic health: a randomized controlled trial
Kate Bermingham et al. · Nature Medicine · 2024
DOI 10.1038/s41591-024-02951-6
rct · n=347Cited 117×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- An 18-week personalized dietary program (PDP) based on postprandial glucose, triglycerides, microbiome, and health history significantly reduces triglycerides, body weight, waist circumference, and HbA1c compared to standard USDA dietary guidelines.Strong
- High adherence to a personalized dietary program significantly reduces LDL cholesterol and apolipoprotein B, whereas standard dietary advice does not, suggesting personalization may be necessary for lipid management in certain individuals.Good
Related findings · Mixed
- Bariatric surgery (VSG and RYGB) is the most effective and sustainable treatment for obesity, producing marked and sustained weight loss that non-surgical interventions cannot match.Strong
- Severely protein-deficient diets (2–3% energy) induce lean body mass loss and metabolic imbalance, whereas adequate protein intake (0.66 g/kg/d minimum) is a prerequisite for maintaining muscle, bone, and physiological function.Strong
- For patients with Class III obesity (BMI >39.9 kg/m2), metabolic bariatric surgery (MBS) is significantly more effective than any currently approved medication, with BilioPancreatic Diversion (BPD) showing the highest estimated weight loss.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →