Research
Cellular
The study reported no substantial differences in the numbers of adverse events between the two groups.
Both dietary approaches appear to be safe with respect to adverse events.
StrongSupportsmedium confidence
In addition, there were no substantial differences between the groups in the numbers of adverse events.
Why this rating
Based on a randomized controlled trial design.
Source
Calorie Restriction with or without Time-Restricted Eating in Weight Loss
Deying Liu et al. · New England Journal of Medicine · 2022
DOI 10.1056/nejmoa2114833
rct · n=139Cited 492×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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- Time-restricted eating resulted in a mean weight loss of -8.0 kg, while daily calorie restriction resulted in a mean weight loss of -6.3 kg after 12 months.Strong
- There were no significant differences in changes in waist circumference, BMI, body fat, or metabolic risk factors between the two groups.Strong
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