Metabolic adaptation

Obesity was associated with an increased risk of early-onset colorectal cancer (CRC) among women, with a multivariable relative risk (RR) of 1.93 for obese women (BMI ≥30.0).

Practitioners should consider obesity as a significant risk factor for early-onset CRC in women.

StrongSupportsmedium confidence

Compared with women with a BMI of 18.5 to 22.9, the multivariable RR was 1.93 (95% CI, 1.15-3.25) for obese women (BMI, ≥30.0).

Po‐Hong Liu et al. · JAMA Oncology · 2018

Why this rating

Based on a large prospective cohort study design.

Source

Association of Obesity With Risk of Early-Onset Colorectal Cancer Among Women

Po‐Hong Liu et al. · JAMA Oncology · 2018

cohort · n=85256Cited 514×

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