Research
Molecular
Caloric restriction-induced transcriptional reprogramming in adipose tissue implicated pathways regulating mitochondrial bioenergetics, anti-inflammatory responses, and longevity.
Caloric restriction may promote metabolic health through specific molecular pathways.
StrongSupportsmedium confidence
CR-induced transcriptional reprogramming in adipose tissue implicated pathways regulating mitochondrial bioenergetics, anti-inflammatory responses, and longevity.
Why this rating
The study provides insights into molecular changes due to caloric restriction.
Source
Caloric restriction in humans reveals immunometabolic regulators of health span
Olga Spadaro et al. · Science · 2022
DOI 10.1126/science.abg7292
cohortCited 297×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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