Research
Cellular
TFA consumption increases the risk of clinical coronary heart disease (CHD).
Awareness of TFA's role in increasing CHD risk is essential for dietary recommendations.
StrongSupportsmedium confidence
Consistent evidence from prospective observational studies of habitual TFA consumption and retrospective observational studies using TFA biomarkers indicates that TFA consumption increases risk of clinical coronary heart disease (CHD).
Why this rating
Supported by consistent evidence from observational studies.
Source
Consumption and Health Effects of Trans Fatty Acids: A Review
Shyam Mohan Teegala et al. · Journal of AOAC International · 2009
DOI 10.1093/jaoac/92.5.1250
reviewCited 133×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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