Research
Cellular
A single bout of lengthening muscle contractions activates satellite cells (SCs), with a peak increase of approximately 80% at 72 hours post-exercise compared to baseline.
Practitioners can utilize lengthening contractions in training to enhance muscle recovery and growth.
StrongSupportsmedium confidence
the number of SCs [neural cell adhesion molecule (NCAM)-labeled cells] expressed relative to total myonuclei... peaked at T72 (approximately 80% increase vs. PRE, P<0.05).
Why this rating
The study involves a controlled exercise intervention with measurable outcomes.
Source
Hepatocyte growth factor (HGF) and the satellite cell response following muscle lengthening contractions in humans
Ciara E. O’Reilly et al. · Muscle & Nerve · 2008
DOI 10.1002/mus.21146
cohort · n=8Cited 109×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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