Research
Cellular
Rosiglitazone treatment exacerbated lipid accumulation and decreased insulin-stimulated glucose transport in skeletal muscle.
Caution is advised when using rosiglitazone, as it may worsen lipid metabolism and insulin sensitivity.
StrongRefutesmedium confidence
In contrast, rosiglitazone treatment exacerbated lipid accumulation and decreased insulin-stimulated glucose transport in skeletal muscle.
Why this rating
The study design involved controlled interventions in an animal model.
Source
Tissue-Specific Effects of Rosiglitazone and Exercise in the Treatment of Lipid-Induced Insulin Resistance
Sarah J. Lessard et al. · Diabetes · 2007
DOI 10.2337/db06-1065
otherCited 103×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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